As you know the trainer has no problem. at least it didn't.
So the best way that we would recommended is : Trainer Troubleshooting.
www.cheathappens.com/trainer_troubleshooting.asp
Unfortunately, yes, it seems like it does.
I'd been using the trainer from here since day one with no issues. I use a lot of trainers here and have for some time and I'm quite sure to always check the literature, the troubleshooting, and make sure my system is as current as can be on drivers.
I purchased the game via retail although we all know it uses Steam anyways.
Since that time I've taken down whatever patch updates they put out and I bought all the DLC. I took some time off to play some other games. When I came back I discovered the same issue. The second I pressed F1 the game would shut down on cue at any point I decided to hit F1. Menu, in game, whenever.
So I figured I had an older trainer and I did. So I happily and confidently updated to the latest one they have here right now and guess what?
The problem didn't go away. I guess it's the trainer. The behavior seems to suggest it for whatever reason.
Everything's fine with the game until I hit F1 then it goes down on cue, like clockwork, every single time.
Try shutting off AV(as well as anyother program that would block a trainer) or running as admin.
Otherwise it's not the trainer, because you two arent the only ones who downloaded it.
I'm always running as Admin on my machine but I'll shut down the AV and any other possible program I can think of for grins. Can't hurt.