it comes out in november 2009 i don't think it continues from res 4 because it's not the same guy.
I heard it came out in March, but the guy at Gamestop could of been wrong, but still, they have been having trailers for this game since a month or 2 after RE 4.
"Capcom has finally disclosed the official Resident Evil 5 release date as being Friday, March 13th 2009."
And then watch there be a month or 2 delay.