RTX3080 and 3090 here, latest Nvidia drivers fixed some issues like you mentioned. I used the International driver pack option for drivers. All probs with trainer (at least for my 2 pc's) disappeared. Hope it helps.
Popping back in because I've re-visited the game since the DLC come out.
Still have the same problem now with the latest drivers, clean Windows install and a second RTX 3090, the first Inno3D 3090 was so loud and hot, got a EVGA 3090 XC3 Hybrid.
Same PC setup 10900k/z490 Hero.
I don't have any issues with any other games, it seems to be a kernel level crash so all I can think of is my BIOS is still in beta for re-bar support.
Played through RE8 with trainer, no problem, same with Days Gone, did experience the Mass Effect 3 trainer crash that was fixed, so I'm at a loss.
I do have a Samsung Odyssey G7 240Hz, which the Mass Effect Legendary hated it running at 240Hz (Mass Effect 1 & 2).
I can pound my system with every stress test, and benchmark all day without issues.
Few things I'm going to try today like removing Afterburner, and updating to the newly released BIOS.