I did it in my Documents folder (Made a folder for my CheatHappens trainer manager and added it to the exclusions) and all my trainers are saved there. I had an issue with a trainer before and this is what solved it. I even checked my exceptions to make sure the folder was still listed there. I honestly don't know why this is happening, it seems to me like the antivirus program is ignoring the exception or something. I think PWizard is right and it's something to do with the AV.
Have you tried it separately from the Trainer Manager, setup exclusions and just run it manually to see if there's a different result? If it's ignoring your preferences and settings, Wiz is absolutely right, of course. Tell the Devs you're unhappy and ask them for a solution.
[Edited by Jaks, 4/15/2020 8:50:05 AM]