Just checked and TruePlay is already off. The game seems to detect any background program running (even tried CoSMOS) and kicks me off. The first message is a warning stating: A running process may be interfering with the correct operation of State of Decay 2... Then the second message says Check for update failed: The signed in users do not have a license for this game...
Are you logged into your Windows Store account and is it linked to the user account being used on the computer?
Yes, I'm logged into the Windows Store and the account is tied to this computer. It runs fine if it's running by itself (ie. no trainer or CoSMOS).
Try running the game .exe as an admin.