Just to let you know premium trainer/ mega trainer dont work on Win 7 64 bit
even with a/virus turned off & run as admin. It crashes.
Just as 0X90 asked, I'm also curious which AV and/or malware product you use?
I'm also on Win-7, 64 Bit, using MS Security Essentials and the Free Malwarebytes and almost every trainer I use works perfectly and has the last several years. I have an occasional burp with a feature once in a great while but normally they work fine.
If you use an additional AV product, have you tried the steps in the detailed information listed for the various apps here?
Link