Ran into an issue with the trainer and Xbox controller. It seems if you start the game and use the xbox controller to navigate the menus and such, after pressing F1 at the main menu and hearing the trainer activated sound, once you got in game no options would activate. Closing the game and trainer then restarting them as normal, and using only the mouse and or keyboard to start the game solved that for me. Once you are in the game and can move your character then you can use the controller and trainer together.
Could be an isolated incident, just thought I'd let you all know.
I'm using an X-Box controller as well, but I didn't have the same incident. Are you running the game in a window or full-screen? I did window if you want to try it that way and see if it works better.
Thanks for the Trainer PWizard, however it does not seem to work for the Steam version of RE?
I pressed F1 several times at the main menu and it does not activate?
Any ideas?
trainer was created using the steam version
best,
Cal