Option 6 and 8 say 'activated' and then 'deactivated' in a few seconds.
That's how they work. From the Readme text file:
Numpad 6: Easy Kills - while this is active, most enemies will be much
more easy to kill. Press key and make your shot. It is only
active for about 3 seconds and turns back off when you hear
"Deactivated". You can use this to kill annoying enemies
that require multiple shots. May not work on all enemies or
turrets.
Numpad 8: No Reload - To use this, press the option key and then shoot
the current weapon once. Wait for 'Deactivated' and then
The next shot you will have a larger ammo clip for that weapon.