I have the same thing. When I try to use the various options of the trainer, the "activated" sound is played but nothing happens ingame. Then, either within a few minutes of playing or when trying the options too often, the game crashes. I only have the Ubisoft version and I cannot find wich version I have but I assume it's the latest version.
Please make sure to have our latest trainer and the latest game version. As Ubisoft Digital is the default setting of the trainer you should be good.
What's your security software and do you have created the exclusions I mentioned on the previous page?
... and the Work folder in this location here -> C:\Users\YourWindowsUserName\Cheathappens\ ...
Just added the work folder, now for the last three tries, the game crashes at startup
Please zip/rar your game exe file for the singleplayer and upload it here.
I assume you mean this file? I usually launch the game from Uplay using the Uplay icon on my desktop.